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Article

Diagnosis of α0-thalassemia Chiang Rai (--CR) deletion by melt curve analysis in Northern Thailand.

Scandinavian journal of clinical and laboratory investigation - 1 May 2022

Ruengdit Chedtapak, Khamphikham Pinyaphat, Punyamung Manoo, Pongpunyayuen Panida, Pornprasert Sakorn

Abstract excerpt

A large novel 44.6 kb deletion named α0-thalassemia Chiang Rai (--CR) was first described in the individuals with uncommon Hb Bart's hydrops fetalis and HbH disease. This study aimed to develop a real-time gap PCR and melt curve analysis for the detection of --CR and investigate its frequency in northern Thailand. Among 4,952 blood samples, the assay was performed in 525 samples with a mean corpuscular volume...

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Identifiers

PMID: 35188019
DOI: 10.1080/00365513.2022.2040049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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