Article
[Associations between Ser447Ter gene polymorphism of lipoprotein lipase and atherosclerotic cerebral infarction].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Oct 2006
Guan Guo-dong, Xu En, Wang Xiao-juan, Xu Yin-hong, Qiu Shao-dong
Abstract excerpt
OBJECTIVE: To investigate the relationship between lipoprotein lipase (LPL) gene Ser447Ter polymorphism and atherosclerotic cerebral infarction (CI), and to investigate the effect of Ser447Ter polymorphism on plasma lipids, carotid intima-media thickness (IMT) and carotid artery plaque (CAP) in patients with CI. METHODS: PCR-restriction fragment lengh polymorphism (PCR-RFLP) technique was used to detect LPL gene...
Topics
- Adult
- Aged
- Alleles
- Cerebral Infarction
- Cholesterol, HDL
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Lipoprotein Lipase
- Male
- Middle Aged
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length
- Triglycerides