Article
Polymorphism in methylenetetrahydrofolate reductase, plasminogen activator inhibitor-1, and apolipoprotein E in hemodialysis patients.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia - 1 Nov 2008
Al-Muhanna Fahad, Al-Mueilo Samir, Al-Ali Amein, Larbi Emmanuel, Rubaish Abdullah, Abdulmohsen Mohammed Fakhry, Al-Zahrani Alhussain, Al-Ateeq Suad
Abstract excerpt
The methylenetetrahydrofolate reductase (MTHFR) gene polymorphism, apolipoprotein E (apo epsilon4) gene polymorphism and polymorphism of plasminogen activator inhibitor-1 (PAI-1) have been shown to be associated with end-stage renal disease (ESRD). To determine the prevalence of these mutations in Saudi patients with ESRD on hemodialysis, we studied the allelic frequency and genotype distribution in patients...
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