Article
A biophysical model for estimating the frequency of radiation-induced mutations resulting from chromosomal translocations.
Advances in space research : the official journal of the Committee on Space Research (COSPAR) - 1 Jan 2001
Wu H, Durante M
Abstract excerpt
Gene mutations can be induced by radiation as a result of chromosomal translocations. A biophysical model is developed to estimate the frequency of this type of mutation induced by low-LET radiation. Mutations resulting from translocations are assumed to be formed by misrejoining of two DNA double strand breaks (DSB), one within the gene and one on a different chromosome. The chromosome containing the gene is...
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