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Article

Chromosome aberrations induced by light ions: Monte Carlo simulations based on a mechanistic model

1 Jan 1999

Abstract excerpt

PURPOSE: To investigate the mechanisms underlying the induction of chromosome aberrations by ionizing radiation, focusing attention on DNA damage severity, interphase chromosome geometry and the distribution of DNA strand breaks. METHODS: An ab initio biophysical model of aberration induction in human lymphocytes specific for light ions was developed, based on the assumption that 'complex lesions' (clustered DNA...

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PMID: 9972789
DOI: 10.1080/095530099140780

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