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Article

Identification of a mutation in the human raloxifene response element of the transforming growth factor-beta 3 gene.

Journal of Korean medical science - 1 Oct 2001

Han K O, Kang Y S, Hwang C S, Moon I G, Yim C H, Chung H Y, Jang H C, Yoon H K, Han I K, Choi Y K

Abstract excerpt

The human transforming growth factor-beta 3 (TGF-beta 3) is an important cytokine to maintain bone mass by inhibiting osteoclast differentiation. Recently raloxifene response element (RRE), a new enhancer with a polypurine sequence for estrogen receptor (ER)-mediated gene activation, was identified on the TGF-beta 3 gene. Functional analysis of the RRE-mediated pathway has shown that this would be an important...

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Identifiers

PMID: 11641521
DOI: 10.3346/jkms.2001.16.5.549
PMCID: PMC3057605

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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