Article
The zinc finger domain of the archaeal minichromosome maintenance protein is required for helicase activity.
The Journal of biological chemistry - 28 Dec 2001
Poplawski A, Grabowski B, Long S E, Kelman Z
Abstract excerpt
The minichromosome maintenance (MCM) proteins, a family of six conserved polypeptides found in all eukaryotes, are essential for DNA replication. The archaeon Methanobacterium thermoautotrophicum Delta H contains a single homologue of MCM with biochemical properties similar to those of the eukaryotic enzyme. The amino acid sequence of the archaeal protein contains a putative zinc-binding domain of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
