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Article

Structure and regulatory role of the C-terminal winged helix domain of the archaeal minichromosome maintenance complex.

Nucleic acids research - 11 Mar 2015

Wiedemann Christoph, Szambowska Anna, Häfner Sabine, Ohlenschläger Oliver, Gührs Karl-Heinz, Görlach Matthias

Abstract excerpt

The minichromosome maintenance complex (MCM) represents the replicative DNA helicase both in eukaryotes and archaea. Here, we describe the solution structure of the C-terminal domains of the archaeal MCMs of Sulfolobus solfataricus (Sso) and Methanothermobacter thermautotrophicus (Mth). Those domains consist of a structurally conserved truncated winged helix (WH) domain lacking the two typical 'wings' of...

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PMID: 25712103
DOI: 10.1093/nar/gkv120
PMCID: PMC4357721

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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