Article
Interallelic complementation at the Drosophila melanogaster gastrulation defective locus defines discrete functional domains of the protein.
Genetics - 1 Oct 2001
Ponomareff G, Giordano H, DeLotto Y, DeLotto R
Abstract excerpt
The gastrulation defective (gd) locus encodes a novel serine protease that is involved in specifying the dorsal-ventral axis during embryonic development. Mutant alleles of gd have been classified into three complementation groups, two of which exhibit strong interallelic (intragenic) complementation. To understand the molecular basis of this interallelic complementation, we examined the complementation behavior...
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