Article
Human cytomegalovirus (HCMV) UL139 open reading frame: Sequence variants are clustered into three major genotypes.
Journal of medical virology - 1 Apr 2006
Qi Ying, Mao Zhi-Qin, Ruan Qiang, He Rong, Ma Yan-Ping, Sun Zheng-Rong, Ji Yao-Hua, Huang Yujing
Abstract excerpt
Human cytomegalovirus (HCMV) infects a number of organs and cell types, leading to the hypothesis that HCMV disease and tissue tropism may be related to specific sequence variability. This study examined the genomic variability of a new polymorphic locus in HCMV, UL139 open reading frame (ORF). Detailed analysis showed that a large number of nucleotide insertions and non-synonymous substitutions occurred in the...
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