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Article

The genes encoding the gCIII complex of human cytomegalovirus exist in highly diverse combinations in clinical isolates.

Journal of virology - 1 Nov 2002

Rasmussen Lucy, Geissler Aimee, Cowan Catherine, Chase Amanda, Winters Mark

Abstract excerpt

The UL74 (glycoprotein O [gO])-UL75 (gH)-UL115 (gL) complex of human cytomegalovirus (CMV), known as the gCIII complex, is likely to play an important role in the life cycle of the virus. The gH and gL proteins have been associated with biological activities, such as the induction of virus-neutralizing antibody, cell-virus fusion, and cell-to-cell spread of the virus. The sequences of the two gH gene variants,...

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Identifiers

PMID: 12368327
DOI: 10.1128/jvi.76.21.10841-10848.2002
PMCID: PMC136653

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