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Article

Dynamic DNA methylation change in the CpG island region of p15 during human myeloid development.

The Journal of clinical investigation - 1 Oct 2001

Sakashita K, Koike K, Kinoshita T, Shiohara M, Kamijo T, Taniguchi S, Kubota T

Abstract excerpt

We examined the kenetics of p15 methylation and expression during myeloid development. We treated human cord blood CD34+ cells with either GM-CSF alone or in combination with stem cell factor and followed methylation at this locus using bisulfite genomic sequencing. CD34+ cells were found to be either fully methylated or completely unmethylated at 27 CpG dinucleotide sites in exon 1 and at 18 CpG sites in the...

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Source

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Identifiers

PMID: 11602627
DOI: 10.1172/JCI13030
PMCID: PMC209528

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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