Article
Glucose metabolism and regulation of glycolysis in Lactococcus lactis strains with decreased lactate dehydrogenase activity.
Metabolic engineering - 1 Jul 2001
Garrigues C, Goupil-Feuillerat N, Cocaign-Bousquet M, Renault P, Lindley N D, Loubiere P
Abstract excerpt
The distribution of carbon flux at the pyruvate node was investigated in Lactococcus lactis under anaerobic conditions with mutant strains having decreased lactate dehydrogenase activity. Strains previously selected by random mutagenesis by H. Boumerdassi, C. Monnet, M. Desmazeaud, and G. Corrieu (Appl. Environ. Microbiol. 63, 2293-2299, 1997) were found to have single punctual mutations in the ldh gene and...
Topics
- Base Sequence
- Biomedical Engineering
- DNA Primers
- Fermentation
- Genes, Bacterial
- Glucose
- Glycolysis
- Kinetics
- L-Lactate Dehydrogenase
- Lactococcus lactis
- Mutation
