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Virulence of swine vesicular disease virus is determined at two amino acids in capsid protein VP1 and 2A protease.

Virus research - 28 Nov 2001

Kanno T, Mackay D, Wilsden G, Kitching P

Abstract excerpt

To identify the genetic determinants of virulence for swine vesicular disease virus, a panel of recombinant and site-directed mutant viruses were constructed from cDNA clones of a virulent J1'73 strain and an avirulent H/3'76 strain. Initial studies mapped the genetic determinants of virulence to either or both of the two sites at nucleotide (nt) 2842, encoding VP1-132, and nt 3355, encoding 2A-20. To determine...

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PMID: 11597755
DOI: 10.1016/s0168-1702(01)00341-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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