Article
Aggressive phenotypic and genotypic features in pediatric and NF2-associated meningiomas: a clinicopathologic study of 53 cases.
Journal of neuropathology and experimental neurology - 1 Oct 2001
Perry A, Giannini C, Raghavan R, Scheithauer B W, Banerjee R, Margraf L, Bowers D C, Lytle R A, Newsham I F, Gutmann D H
Abstract excerpt
Pediatric and NF2-associated meningiomas are uncommon and poorly characterized in comparison to sporadic adult cases. In order to elucidate their molecular features, we analyzed MIB-1, progesterone receptor (PR), NF2, merlin, DAL-1, DAL-1 protein, and chromosomal arms 1p and 14q in 53 meningiomas from 40 pediatric/NF2 patients using immunohistochemistry and dual-color fluorescence in situ hybridization (FISH)....
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