Article
Linkage disequilibrium and haplotype analysis among four novel single-nucleotide polymorphisms in the human leukemia inhibitory factor (LIF) gene.
Journal of human genetics - 1 Jan 2001
Ishida R, Ezura Y, Iwasaki H, Nakazawa I, Kajita M, Kodaira M, Ito H, Emi M
Abstract excerpt
Leukemia inhibitory factor (LIF) is a pleiotropic cytokine implicated in various pathological conditions, such as rheumatoid arthritis and osteoporosis. Despite the possible importance of LIF as a therapeutic target, little is known about the bioregulation of the human LIF gene. We here sequenced the entire structure of the LIF gene of 48 alleles in the Japanese population. These experiments identified four...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
