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Article

Fine mapping of canine XLPRA establishes homology of the human and canine RP3 intervals.

Investigative ophthalmology & visual science - 1 Oct 2001

Zhang Q, Acland G M, Zangerl B, Johnson J L, Mao Z, Zeiss C J, Ostrander E A, Aguirre G D

Abstract excerpt

PURPOSE: Canine X-linked progressive retinal atrophy (XLPRA) is a hereditary, progressive retinal degeneration that has been mapped previously to the canine X chromosome in a region flanked by the dystrophin (DMD) and tissue inhibitor of metalloproteinase 1 (TIMP1) genes, and is tightly linked to the gene RPGR. The comparable region of the human X chromosome includes the disease locus for RP3, an X-linked form of...

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Source

Identifiers

PMID: 11581184

Genes

RPGR
DMD
OTC
TIMP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Fine mapping of canine XLPRA establishes homology of the human and canine RP3 intervals.PMID 11581184Read ↗

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Linkage analysis and comparative mapping of canine progressive rod-cone degeneration (prcd) establishes potential locus homology with retinitis pigmentosa (RP17) in humans.Semantic proximity Read ↗

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XLPRA: a canine retinal degeneration inherited as an X-linked trait.Semantic proximity Read ↗

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Candidate Genetic Modifiers for RPGR Retinal Degeneration.Semantic proximity Read ↗

Mutational hot spot within a new RPGR exon in X-linked retinitis pigmentosa.Semantic proximity Read ↗

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