Article
Glucose catabolism in the rabbit VX2 tumor model for liver cancer: characterization and targeting hexokinase.
Cancer letters - 8 Nov 2001
Ko Y H, Pedersen P L, Geschwind J F
Abstract excerpt
The rabbit VX2 tumor when implanted in the liver has proven convenient as a model for studying hepatocellular carcinomas. However, its metabolic properties have not been well studied. Significantly, studies described here show that the VX2 tumor exhibits a high glycolytic/high hexokinase phenotype that is retained following implantation and growth in rabbit liver. In addition, results of a limited screen show...
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