Article
Characterization of the annexin I gene and evaluation of its role in type 2 diabetes.
Diabetes - 1 Oct 2001
Lindgren C M, Nilsson A, Orho-Melander M, Almgren P, Groop L C
Abstract excerpt
In a previous study, we identified suggestive linkage between type 2 diabetes and a locus on chromosome 9p13-q21. This region contains the gene annexin I (ANXA1), encoding a protein suggested to be involved in both insulin secretion and insulin action. In this study, we sequenced the exon/intron boundaries of the human ANXA1 gene and performed mutation screening in 41 individuals from the initial linkage study....
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