Resolution of the two loci for autosomal dominant aniridia, AN1 and AN2, to a single locus on chromosome 11p13.

doi:10.1016/0888-7543(92)90002-a

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Article

Resolution of the two loci for autosomal dominant aniridia, AN1 and AN2, to a single locus on chromosome 11p13.

Genomics - 1 Aug 1992

Lyons L A, Martha A, Mintz-Hittner H A, Saunders G F, Ferrell R E

Abstract excerpt

Two distinct loci have been proposed for aniridia; AN1 for autosomal dominant aniridia on chromosome 2p and AN2 for the aniridia in the WAGR contiguous gene syndrome on chromosome 11p13. In this report, the kindred segregating for autosomal dominant aniridia, which suggested linkage to acid phosp...

Topics

Alkaline Phosphatase
Aniridia
Chromosome Mapping
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 2
Female
Genes, Dominant
Genetic Linkage
Genetic Markers
Genotype
Humans
Male
Pedigree
Polymorphism, Genetic

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