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Article

The HOXD8 locus (2q31) is linked to type I diabetes. Interaction with chromosome 6 and 11 disease susceptibility genes.

Diabetes - 1 Jan 1995

Owerbach D, Gabbay K H

Abstract excerpt

Type I diabetes susceptibility genes have been identified within the major histocompatibility complex (MHC) on chromosome 6p21.3 and near the VNTR/insulin region on chromosome 11p15.5. We have used polymorphic dinucleotide repeat markers to search the human genome for additional susceptibility genes in 162 type I diabetic families with an affected sibling pair. We report that an additional susceptibility gene is...

Topics

Alleles
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 6
Diabetes Mellitus, Type 1
Family Health
Genes, Homeobox
Genetic Linkage
Genetic Predisposition to Disease
Haplotypes
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7813807
DOI: 10.2337/diab.44.1.132

Genes

HOXD8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7813807-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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