Article
Specificity of the fivefold increase in AD in mothers of adults with Down syndrome.
Neurology - 25 Sept 2001
Schupf N, Kapell D, Nightingale B, Lee J H, Mohlenhoff J, Bewley S, Ottman R, Mayeux R
Abstract excerpt
BACKGROUND: In a previous study, the authors found that the risk of AD among mothers who were 35 years or younger when their children with Down syndrome (DS) were born was five times that of mothers of children with other forms of mental retardation. The current study investigated the specificity of the familial aggregation of DS and AD by examining whether mothers who gave birth to children with DS before age 35...
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