Article
Alzheimer’s disease in people with Down’s syndrome: the prospects for and the challenges of developing preventative treatments
24 Oct 2016
Abstract excerpt
People with Down's syndrome (DS) are at high risk for developing Alzheimer's disease (AD) at a relatively young age. This increased risk is not observed in people with intellectual disabilities for reasons other than DS and for this reason it is unlikely to be due to non-specific effects of having a neurodevelopmental disorder but, instead, a direct consequence of the genetics of DS (trisomy 21). Given the...
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