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Article

Molecular Basis of Cell-specific Endothelial Nitric-oxide Synthase Expression in Airway Epithelium

1 Mar 2000

Abstract excerpt

Nitric oxide (NO) plays an important role in airway function, and endothelial NO synthase (eNOS) is expressed in airway epithelium. To determine the basis of cell-specific eNOS expression in airway epithelium, studies were performed in NCI-H441 human bronchiolar epithelial cells transfected with the human eNOS promoter fused to luciferase. Transfection with 1624 base pairs of sequence 5' to the initiation ATG...

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PMID: 10713142
DOI: 10.1074/jbc.275.11.8183

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