Article
Mapping the Transcriptional Machinery of the IL-8 Gene in Human Bronchial Epithelial Cells
27 Oct 2011
Abstract excerpt
IL-8 released from bronchial epithelial cells infected with Pseudomonas aeruginosa plays a crucial role in the chronic lung pathology of patients affected by cystic fibrosis. Novel anti-inflammatory approaches will benefit from a thorough understanding of the regulatory mechanisms involved in the transcription of this chemokine to identify potential pharmacological targets. We addressed this issue by...