Article
Detection of recombination in DNA multiple alignments with hidden Markov models.
Journal of computational biology : a journal of computational molecular cell biology - 1 Jan 2001
Husmeier D, Wright F
Abstract excerpt
Conventional phylogenetic tree estimation methods assume that all sites in a DNA multiple alignment have the same evolutionary history. This assumption is violated in data sets from certain bacteria and viruses due to recombination, a process that leads to the creation of mosaic sequences from different strains and, if undetected, causes systematic errors in phylogenetic tree estimation. In the current work, a...
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