Discriminating between rate heterogeneity and interspecific recombination in DNA sequence alignments with phylogenetic factorial hidden Markov models.

Abstract excerpt

MOTIVATION: A recently proposed method for detecting recombination in DNA sequence alignments is based on the combination of hidden Markov models (HMMs) with phylogenetic trees. Although this method was found to detect breakpoints of recombinant regions more accurately than most existing techniques, it inherently fails to distinguish between recombination and rate variation. In the present paper, we propose to...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Algorithms
• Share to Discriminant Analysis
• Share to Evolution, Molecular