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Article

Common polymorphisms in the glyoxalase-1 gene and their association with pro-thrombotic factors.

Diabetes & vascular disease research - 1 May 2004

Gale Christopher P, Futers T Simon, Summers Lucinda K M

Abstract excerpt

Advanced glycation endproducts (AGEs) form at an accelerated rate in diabetes and contribute to the development of macrovascular disease. Their precursors are detoxified by the glyoxalase system. Perturbations of the glyoxalase-1 gene may alter AGEs' interactions and affect pro-thrombotic factors. We screened the glyoxalase-1 gene for mutations and measured pro-thrombotic markers in 537 subjects from 89 healthy...

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Identifiers

PMID: 16305054
DOI: 10.3132/dvdr.2004.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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