Article
Brain membrane phospholipid alterations in Alzheimer's disease.
Neurochemical research - 1 Jul 2001
Pettegrew J W, Panchalingam K, Hamilton R L, McClure R J
Abstract excerpt
Studies have demonstrated alterations in brain membrane phospholipid metabolite levels in Alzheimer's disease (AD). The changes in phospholipid metabolite levels correlate with neuropathological hallmarks of the disease and measures of cognitive decline. This 31P nuclear magnetic resonance (NMR) study of Folch extracts of autopsy material reveals significant reductions in AD brain levels of...
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