Article
Classification of the kinetics of factor VIII inhibitors in haemophilia A: plasma dilution studies are more discriminatory than time-course studies.
British journal of haematology - 1 Sept 2001
Ling M, Duncan E M, Rodgers S E, Somogyi A A, Crabb G A, Street A M, Lloyd J V
Abstract excerpt
Factor VIII inhibitors have previously been classified as type I or type II using complex experiments that study the time course of inactivation of factor VIII and the effect of varying the antibody concentration. Classification may be important to better understand inhibitor behaviour in vivo. To determine the most reliable method of classifying the kinetics of factor VIII inactivation, we studied 11 patients...
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