Article
Inhibitors: resolving diagnostic and therapeutic dilemmas.
Haemophilia : the official journal of the World Federation of Hemophilia - 1 May 2002
Dimichele D
Abstract excerpt
The good quality of life now anticipated by individuals with haemophilia A and B can be drastically altered by the unpredictable development of an inhibitor, a polyclonal high-affinity IgG antibody directed against factor VIII or IX. This paper discusses our current state of knowledge about inhibitors within the context of: (1) the extent and nature of the problem, including its incidence and prevalence,...
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