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Article

Epidermal growth factor receptor signaling and the invasive phenotype of ovarian carcinoma cells.

Journal of the National Cancer Institute - 19 Sept 2001

Alper O, Bergmann-Leitner E S, Bennett T A, Hacker N F, Stromberg K, Stetler-Stevenson W G

Abstract excerpt

BACKGROUND: Most (70%-100%) ovarian carcinomas express high levels of the epidermal growth factor receptor (EGFR). To examine the relationship between EGFR and the invasive phenotype, we assessed integrin expression, adhesion, matrix metalloproteinase (MMP) activity, and migration in ovarian cancer cells in which EGFR expression was modified. METHODS: NIH:OVCAR-8 human ovarian carcinoma cells were transfected...

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PMID: 11562388
DOI: 10.1093/jnci/93.18.1375

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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