Article
The pathology of inherited breast cancer.
Pathology - 1 Aug 2002
Armes Jane E, Venter Deon J
Abstract excerpt
Familial breast cancer has been recognised for many years. In the 1990s the genetic mechanism of inheritance of a proportion of these familial cancers was found to be attributable to germline mutation in either of two newly discovered genes, namely BRCA1 and BRCA2. Since the discovery of these genes, studies have been performed in which the pathological characteristics of familial cancers arising in patients with...
Topics
- Breast Neoplasms
- Female
- Genes, BRCA1
- Genes, BRCA2
- Germ-Line Mutation
- Humans
- Phenotype
