Article
The role of promyelocytic leukemia zinc finger and promyelocytic leukemia in leukemogenesis and development
1 Jul 2001
Abstract excerpt
Acute promyelocytic leukemia (APL) was originally distinguished by an extremely poor clinical outcome. In the past few years, however, important progress has been made in defining the molecular basis of APL pathogenesis and in optimizing its treatment to an extent that this leukemia is now considered curable. Two features are unique to this leukemia: its remission after retinoic acid (RA) treatment through...
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