Article
Novel mode of transcription regulation by SdiA, an Escherichia coli homologue of the quorum-sensing regulator.
Molecular microbiology - 1 Sept 2001
Yamamoto K, Yata K, Fujita N, Ishihama A
Abstract excerpt
SdiA, an Escherichia coli homologue of the quorum-sensing regulator, controls the expression of the ftsQAZ operon for cell division. Transcription of ftsQ is under the control of two promoters, upstream ftsQP2 and downstream ftsQP1, which are separated by 125 bp. SdiA activates transcription from ftsQP2 in vivo. Here, we demonstrate that SdiA facilitates the RNA polymerase binding to ftsQP2 and thereby stimulates...
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