Article
Genetics of type 1 diabetes.
Best practice & research. Clinical endocrinology & metabolism - 1 Sept 2001
Kelly M A, Mijovic C H, Barnett A H
Abstract excerpt
Type 1 diabetes mellitus is a T-cell-mediated autoimmune disease characterized by the selective destruction of pancreatic beta cells. Susceptibility to the disease is determined by a combination of genetic and environmental factors. The genetic factors are termed 'susceptibility genes' as they modify the risk of diabetes but are neither necessary nor sufficient for disease to develop. A large number of...
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