Article
The genetic architecture of type 1 diabetes mellitus.
Molecular and cellular endocrinology - 5 Dec 2018
Nyaga Denis M, Vickers Mark H, Jefferies Craig, Perry Jo K, O'Sullivan Justin M
Abstract excerpt
Type 1 diabetes mellitus (T1D) is a complex autoimmune disorder characterised by loss of the insulin-producing pancreatic beta cells in genetically predisposed individuals, ultimately resulting in insulin deficiency and hyperglycaemia. T1D is most common among children and young adults, and the incidence is on the rise across the world. The aetiology of T1D is hypothesized to involve genetic and environmental...
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