Genetic Aspects of type 1 diabetes

doi:10.6065/apem.2019.24.3.143

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Genetic Aspects of type 1 diabetes

27 Sept 2019

Abstract excerpt

Type 1 diabetes mellitus (T1DM) is characterized by autoimmune destruction of pancreatic beta-cells in genetically predisposed individuals, eventually resulting in severe insulin deficiency. It is the most common form of diabetes in children and adolescents. Genetic susceptibility plays a crucial role in development of T1DM. The human leukocyte antigen complex plays a key role in the pathogenesis of T1DM....

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PMID: 31607106
DOI: 10.6065/apem.2019.24.3.143

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