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Article

Leukemia inhibitory factor determines the growth status of injured adult sensory neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Sept 2001

Cafferty W B, Gardiner N J, Gavazzi I, Powell J, McMahon S B, Heath J K, Munson J, Cohen J, Thompson S W

Abstract excerpt

Conditioning injury to adult mammalian sensory neurons enhances their regeneration potential. Here we show that leukemia inhibitory factor (LIF) is a fundamental component of the conditioning response. Conditioning injury in vivo significantly increases the intrinsic growth capacity of sensory neurons in vitro from LIF+/+ mice. This conditioning effect is significantly blunted in sensory neurons from LIF-/- mice....

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Source

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Identifiers

PMID: 11549727
PMCID: PMC6762988

Genes

LIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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