Article
The Q223R polymorphism of the leptin receptor gene is significantly associated with obesity and predicts a small percentage of body weight and body composition variability.
The Journal of clinical endocrinology and metabolism - 1 Sept 2001
Yiannakouris N, Yannakoulia M, Melistas L, Chan J L, Klimis-Zacas D, Mantzoros C S
Abstract excerpt
Genetic variation at the leptin receptor gene locus may play an important role in the pathophysiology of human obesity, a leptin-resistant state. Previous studies exploring potential associations between leptin receptor gene polymorphisms and obesity have reported conflicting results. The aim of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.