Article
Cytokine polymorphic analyses indicate ethnic differences in the allelic distribution of interleukin-2 and interleukin-6.
Transplantation - 27 Aug 2001
Cox E D, Hoffmann S C, DiMercurio B S, Wesley R A, Harlan D M, Kirk A D, Blair P J
Abstract excerpt
BACKGROUND: Polymorphisms in the regulatory regions of cytokine genes affect protein production and are associated with allograft outcome. Ethnic origin has been identified as a significant prognostic factor for several immune-mediated diseases and for outcome after allotransplantation. A clear relationship between cytokine polymorphisms and ethnicity has not been shown. METHODS: One hundred sixty subjects...
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