Article
Ethnicity greatly influences cytokine gene polymorphism distribution.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Jul 2002
Hoffmann Steven C, Stanley Eran M, Cox E Darrin, DiMercurio Barbara S, Koziol Deloris E, Harlan David M, Kirk Allan D, Blair Patrick J
Abstract excerpt
Polymorphisms in the regulatory regions of cytokine genes are associated with high and low cytokine production and may modulate the magnitude of alloimmune responses following transplantation. Ethnicity influences allograft half-life and the incidence of acute and chronic rejection. We have questioned whether ethnic-based differences in renal allograft survival could be due in part to inheritance of cytokine...
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