Article
The HA-2 minor histocompatibility antigen is derived from a diallelic gene encoding a novel human class I myosin protein.
Journal of immunology (Baltimore, Md. : 1950) - 15 Sept 2001
Pierce R A, Field E D, Mutis T, Golovina T N, Von Kap-Herr C, Wilke M, Pool J, Shabanowitz J, Pettenati M J, Eisenlohr L C, Hunt D F, Goulmy E, Engelhard V H
Abstract excerpt
Human minor histocompatibility Ags (mHag) present significant barriers to successful bone marrow transplantation. However, the structure of human mHag and the basis for antigenic disparities are still largely unknown. Here we report the identification of the gene encoding the human mHag HA-2 as a previously unknown member of the class I myosin family, which we have designated MYO1G. The gene is located on the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.