Article
Mapping of quantitative trait loci with knockout/congenic strains.
Genome research - 1 Sept 2001
Bolivar V J, Cook M N, Flaherty L
Abstract excerpt
Recently we have explored the use of knockout/congenic mouse strains for isolating and mapping quantitative trait loci (QTLs). Because most knockout strains have been bred to be B6.129 congenic strains, they can be used to test for QTLs in the targeted chromosomal area as long as there is a genetic difference between B6 and 129. Thus, we have tested a number of knockout/congenic strains in a series of behavioral...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
