Article
The PlA1/A2 polymorphism of platelet glycoprotein IIIa is not associated with deep venous thrombosis.
International angiology : a journal of the International Union of Angiology - 1 Jun 2001
Renner W, Winkler M, Hoffmann C, Köppel H, Seinost G, Brodmann M, Pilger E
Abstract excerpt
BACKGROUND: Platelet glycoprotein (GP) IIb/IIIa, a fibrinogen and von Willebrand factor binding membrane receptor, has an important role in platelet aggregation. A common leucine33-proline polymorphism (PlA1/A2) of the gene encoding the GP IIIa subunit is associated with platelet reactivity and has been proposed as a risk factor for atherothrombotic disease. The aim of this study was to investigate the role of...
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