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Reactivation and Lytic Replication of Kaposi’s Sarcoma-Associated Herpesvirus: An Update

20 Apr 2017

Abstract excerpt

The life cycle of Kaposi's sarcoma-associated herpesvirus (KSHV) consists of two phases, latent and lytic. The virus establishes latency as a strategy for avoiding host immune surveillance and fusing symbiotically with the host for lifetime persistent infection. However, latency can be disrupted and KSHV is reactivated for entry into the lytic replication. Viral lytic replication is crucial for efficient...

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PMID: 28473805
DOI: 10.3389/fmicb.2017.00613

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