Article
[Meningococcal purpura fulminans: untoward result of genetic polymorphism?].
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie - 1 Aug 2001
Mercier J C, Bingen E, Schlegel N, Elion J, Casanova J L, Mira J P, Beaufils F
Abstract excerpt
Despite significant progress in intensive care medicine, the mortality of septic shock has not changed in recent years. Early recognition of subtle signs in favor of meningococcal sepsis, early antibiotic treatment, and aggressive hemodynamic support remains the cornerstone of therapy of severe meningococcal shock in children. Recent work has emphasized the role of genetic polymorphisms in various systems to...
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