Article
Effect of the Factor V Leiden mutation on the severity of meningococcal disease.
The Pediatric infectious disease journal - 1 Oct 1999
Kondaveeti S, Hibberd M L, Booy R, Nadel S, Levin M
Abstract excerpt
BACKGROUND: One of the most serious complications of meningococcal disease is the syndrome of purpura fulminans, which is characterized by intravascular thrombosis and hemorrhagic infarction of skin, limbs and digits. The reasons why some patients with meningococcal disease develop purpura fulminans while others have minimal thrombotic and skin involvement despite having profound septic shock are not yet...
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