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Article

Pharmacogenetics of warfarin elimination and its clinical implications.

Clinical pharmacokinetics - 1 Jan 2001

Takahashi H, Echizen H

Abstract excerpt

Warfarin is one of the most widely prescribed oral anticoagulants. However, optimal use of the drug has been hampered by its >10-fold interpatient variability in the doses required to attain therapeutic responses. Pharmacogenetic polymorphism of cytochrome P450 (CYP) may be associated with impair...

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Source

Identifiers

PMID: 11523725
DOI: 10.2165/00003088-200140080-00003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11523725-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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