Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

T lymphocyte-dependent IL-10 down-regulates a cytokine storm driven by Toxoplasma gondii GRA24

23 Oct 2024

Abstract excerpt

ABSTRACT As a model organism in the study of immunity to infection, Toxoplasma gondii has been instrumental in establishing key principles of host anti-microbial defense and its regulation. Here, we employed an attenuated uracil auxotroph strain of Type I Toxoplasma designated OMP to further untangle the early immune response to this parasitic pathogen. Experiments using αβ T cell-deficient Tcrb -/- mice...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Herpesvirus Infections and Treatments
Share to Toxoplasma gondii Research Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39440975
DOI: 10.1128/mbio.01455-24

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

T lymphocyte-dependent IL-10 down-regulates a cytokine storm driven by Toxoplasma gondii GRA24PMID 39440975Read ↗

Lessons from Toxoplasma: Host responses that mediate parasite control and the microbial effectors that subvert themSemantic proximity Read ↗

Novel roles of dense granule protein 12 (GRA12) in Toxoplasma gondii infection.Semantic proximity Read ↗

Toxoplasma gondii GRA60 is an effector protein that modulates host cell autonomous immunity and contributes to virulence.Semantic proximity Read ↗

The induction of acute ileitis by a single microbial antigen of Toxoplasma gondii.Semantic proximity Read ↗

A genome-wide loss-of-function screen identifies <i>Toxoplasma gondii</i> genes that determine fitness in interferon gamma-activated murine macrophagesSemantic proximity Read ↗

GRA12 is a common virulence factor across Toxoplasma gondii strains and mouse subspeciesSemantic proximity Read ↗

Hypermigration of macrophages through the concerted action of GRA effectors on NF-κB/p38 signaling and host chromatin accessibility potentiates <i>Toxoplasma</i> disseminationSemantic proximity Read ↗

Toll-Like Receptor Initiated Host Defense against<i>Toxoplasma gondii</i>Semantic proximity Read ↗

Hypermigration of macrophages through the concerted action of GRA effectors on NF-κB/p38 signaling and host chromatin accessibility potentiates Toxoplasma disseminationSemantic proximity Read ↗

Host immune responses to Toxoplasma gondiiSemantic proximity Read ↗

Genome-wide screens identify Toxoplasma gondii determinants of parasite fitness in IFNγ-activated murine macrophagesSemantic proximity Read ↗

Strategies Developed by Toxoplasma gondii to Survive in the HostSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.